Cipro knee tendon discomfort So I'm taking cipro for testicle pain from a piercing infection. About a month into taking it I was working and repeatedly began bending down to clean/pick … About a month into taking it I was working and repeatedly began bending down to clean/pick … July 8, 2008 -- Federal regulators are ordering new warnings on Cipro and similar antibiotics because of increased risk of tendinitis and tendon rupture. Joint Pain in Children Taking Cipro Cipro has been associated with muscle, joint, or tendon problems when used in children. In one clinical study, Cipro was given to one group of children, while another antibiotic (a cephalosporin medication) was given to a second group. Question. I was on levaquin for 8 days and awoke the same way with knee pain. By the next day I also had arm pain. It is a week later and the pain has not eased. by Loretta (Kansas) Did not have any problems with my knee's until 3 days into taking Cipro for treatment of Lyme disease. Summary. Knee swelling is found among people who take Cipro, especially for people who are female, 60+ old , have been taking the drug for 1 month, also take medication Levaquin, and have Pain. Cipro (ciprofloxacin) is a quinolone antibiotic. Cipro is available as a generic drug and is prescribed to treat infections of the skin, lungs, airways, bones, joints, and urinary tract infections caused by susceptible bacteria. Learn about the potential side effects of Cipro (ciprofloxacin). Includes common and rare side effects information for consumers and healthcare professionals. The CT scan showed an inflamed kidney. The doctor now believes a kidney infection and has prescribed cipro and Tylenol and Ibuprofen for pain. After 5 days, the pain (while not constant) has not diminished. Summary. There is no Knee pain reported by people who take Cipro yet. This review analyzes which people have Knee pain with Cipro. It is created by eHealthMe based on reports from FDA, and is updated regularly.